A colleague in food science recently sent me a narrative review outlining some of the challenges in their field (Cassidy and Minihane, 2017, Am J Clin Nutr). One of these was “extensive heterogeneity in the response to increased intake [of flavonoids]”.
Beautifully written Darren. Thanks for exposing the HTE smokescreen that so many investigators are throwing up nowadays. The only way to assess responses in individual patients is to have a 6-period 2-treatment randomized crossover study as Senn has eloquently written about.
Beautifully written Darren. Thanks for exposing the HTE smokescreen that so many investigators are throwing up nowadays. The only way to assess responses in individual patients is to have a 6-period 2-treatment randomized crossover study as Senn has eloquently written about.